How long can Wegovy stay out of the fridge?
Wegovy (semaglutide)
Keep it in the fridge. If needed, an unused pen can be kept between 46°F and 86°F for up to 28 days before the cap comes off.
- Best
- Fridge (36°F to 46°F)
- Out of the fridge
- Up to 28 days, 46°F to 86°F
Good to know
- Each single-dose pen is used once, then thrown out.
- Keep it in the original carton to protect it from light.
- Do not freeze.
Source: the FDA label on DailyMed, last checked October 14, 2026. Labels change, so check the product in hand. Questions about a patient's medicine go to the pharmacist.
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