How long can Novolin 70/30 stay out of the fridge?

Novolin 70/30 (NPH and regular insulin)

It depends on the device: vial 42 days, flexpen 28 days at room temperature, opened or not. After that, throw it out even if insulin is left.

Vial
42 days
FlexPen
28 days

Good to know

  • Before opening, keep it in the fridge (36°F to 46°F) until the expiration date on the box.
  • Keep below 86°F (30°C), away from heat and direct light. Never freeze; throw out insulin that froze.
  • Whether an opened pen can go back in the fridge depends on the product. Check the label.

Source: the FDA label on DailyMed, last checked October 14, 2026. Labels change, so check the product in hand. Questions about a patient's medicine go to the pharmacist.

Working out the days supply?

The insulin & GLP-1 days supply calculator counts the in-use limit for you, and tells you how many boxes and pens to give.

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